PEPTIDE THERAPY

Peptide Therapy is an evolving, cutting-edge, medical science in which specific, bio-identical, protein amino acid sequences called “peptides” are used to repair, regenerate, support, and improve the structure and function of different parts of the mind and body.  Well-known examples of naturally occurring human peptides are insulin, ACTH, glucagon, growth hormone, and thyroid hormone.

 

Over 7,000 peptides that are naturally occurring in the body have thus far been identified, and, over 200 medicinal peptides are currently used in clinical medicine. 

 

Peptide Therapy is becoming more popular with Integrative Medicine physicians because Medicinal Peptides are:

 

  • Highly Specific and Very Effective in their Therapeutic Action

  • Typically Very Safe, and

  • Extremely Well Tolerated

 

It is very important to understand the difference between pharmaceutical drugs and medicinal peptides.

 

With conventional, allopathic, pharmaceutical drugs, the mind and body will always have a “reaction" that unfortunately often includes unpleasant, potentially harmful, and sometimes lethal, adverse, side effects.  

 

This is due to the fact that pharmaceutical drugs biochemically ‘force' changes and distortions upon the mind and body to which it too often reacts badly. 

 

In contrast, with bio-identical human medicinal peptides, the mind and body will always have a “response” that is very safe and virtually free of any adverse, side effects when properly prescribed by a well-trained, medical physician certified in peptide therapy.  

 

This is due to the fact that medicinal peptides are “messenger” molecules with which your mind and body are already familiar because they have been in you since you were born. 

 

The cells in your mind and body use the innate, inborn, medicinal peptides to communicate with one another to tell them what to do or not to do.  That is, they guide and balance all the metabolic and regenerative functions that serve to keep us healthy.

 

When properly prescribed and administered by a specially trained physician, medicinal peptides communicate with specific cells, tissues, and vital organs in the body by binding to peptide receptors on the cell surfaces, thereby signaling optimal, cellular messages for health improvement and potentially enhancing the function of the entire body.

 

Peptide Therapy includes many, new, potent, peptide medicines with amazing potential to promote greater health and well-being, and a potentially longer, higher quality of life.

 

Benefits of peptide therapy may include:

 

  • Increased Energy and Stamina

  • Better Mental Focus and Memory

  • Strengthened Immune System Defenses

  • Improved Recovery from Illnesses and Wounds

  • Increased Muscle Mass and Tone

  • Increased Bone Density

  • Improved Skin Elasticity

  • Reduced Wrinkled Skin

  • Fuller Hair

  • Decreased Body Fat and Weight Loss

  • Lowered Cholesterol and Lipid Levels

  • Decreased Joint and Muscle Pain

  • Deeper, Rejuvenating Sleep

  • Enhanced Sex Drive

 

Breakthroughs in modern medicine have shown the benefits of medicinal peptides to aid in the diagnosis and treatment of a wide number of both physical and mental disorders, as identified by the International Peptide Society (IPS), in which we have professional membership.

 

Peptide Therapy may help with a broad range of health conditions, including:

 

  • Anti-Aging and Regeneration of the Entire Body

  • Tissue Repair of Bones, Cartilage, Ligaments, Tendons, Joints, Muscles, and Skin

  • Balancing Endocrine Hormones

  • Enhancing Growth Hormone Production

  • Hair Regrowth and Restoration

  • Inflammatory Diseases, both acute and chronic

  • Arthritis, degenerative and rheumatoid

  • Autoimmune Disorders, e.g., Lupus, MS, Sjogren’s syndrome, etc.

  • Cognitive, Mood and Memory Enhancement

  • Cellular Energy Production and Enhanced Vitality

  • Cytoprotection from Oxidative Stress

  • Alzheimer’s Disease and Dementia

  • Post-Stroke Recovery

  • Obesity and Weight Management

  • Osteopenia  and Osteoporosis

  • Anxiety and Stress Disorders

  • Depression

  • Insomnia

  • Improving Sexual Disorders, Libido, and Erectile Dysfunction

 

Please feel free to call us at (434) 361-1896 to schedule a consultation with Dr. Mitch Fleisher, the Medical Director of the Center for Integrative & Regenerative Medicine, to determine which medicinal peptides would be most appropriate and best to restore your mind and body to its optimal health and well-being.

 

A Word of Caution: 

 

Medicinal peptides should only be obtained from FDA-certified, 503A or 503B,  U.S. compounding pharmacies that provide peptides with greater than 99.8% purity and chemical integrity.  That is, you are receiving the highest quality, FDA-regulated, pharmaceutical grade, medicinal peptides by U.S. law. 

 

Never purchase peptides from online ‘discount’ websites, since they are not regulated, and have been found to be adulterated, substandard, often fraudulent products, which can potentially cause adverse effects and great harm.  The principle of Caveat Emptor (“Buyer Beware”) applies here. 

 

Moreover, peptides are powerful medicines that should and must be carefully prescribed and individually managed by a specially trained, licensed, medical physician who understands the correct peptides and the dosages to be used for different health conditions.  Peptide therapy requires expert medical guidance to experience and benefit from their exceptional therapeutic potential.

 

For educational purposes, here are a few examples of the medicinal peptides that we offer to our patients:

 

BPC 157

 

BPC (Body Protection Compound) 157 is a pentadecapeptide (composed of 15 amino acids) that is naturally produced in the secretions of the gastrointestinal tract.  The body uses it to protect and heal the gastrointestinal mucosal lining from inflammation and injury.  Therefore, BPC 157 has been effectively prescribed for peptic ulcers, acid reflux, GERD, eosinophilic esophagitis, intestinal hyperpermeability (leaky gut syndrome), inflammatory bowel diseases, and, to improve digestive function, to help and protect the liver from toxic insults, and to generally protect and heal inflamed intestinal epithelium.  BPC 157 has also been shown to promote repair and regeneration of injured, inflamed tissues in the bones, cartilage, ligaments, tendons, joints, muscles, and blood vessels, as well as to protect and promote the healing of injured peripheral nerves and brain cells.

 

Benefits of BPC 157 may include:

 

  • Potent, anti-inflammatory properties

  • Improves general digestive function (IBS)

  • Repair and maintenance of GI mucosal integrity

  • Helps to prevent and heal gastric and duodenal ulcers

  • Helps to protect and heal inflamed intestinal epithelium (Leaky Gut Syndrome)

  • Promotes healing in Inflammatory bowel disease (IBD), esp. in exacerbations/flareups

  • Helps to protect and promote healing of liver from toxic insults (alcohol, antibiotics, etc.)

  • Helps to promote tissue repair in the GI tract, brain, bone, ligaments, tendons, joints, muscles, etc.

  • Helps to promote repair of damaged nerves and support healing of peripheral neuropathy

  • Neuro-protective properties, specifically modulating the serotonergic and dopaminergic systems

  • Effective treatment for Traumatic Brain Injury (TBI) and Post-Concussion Syndrome

  • Promotion of angiogenesis and vasculogenesis (new, healthy blood vessel growth)

 

Specific Target Conditions for BPC 157 Peptide Therapy may include:

 

  • Acute and chronic inflammatory conditions

  • GI ulcers and inflammation

  • Inflammatory bowel diseases

  • Leaky Gut Syndrome

  • H. pylori gastrointestinal infections

  • Autoimmune diseases

  • Chronic Allergies

  • Chemical Sensitivity

  • Lyme disease

  • Chronic viral, bacterial and fungal infections with inflammation

  • Chronic Fatigue Syndrome and Fibromyalgia

  • Cardiovascular and cerebrovascular disorders

  • Heart rhythm irregularities (cardiac arrhythmias)

  • Diabetes mellitus and associated chronic problems

  • Post-surgical conditions

  • Peripheral Neuropathy

  • Anti-Aging and Regeneration

 

 

Cerebrolysin

 

Cerebrolysin is a nootropic (cognitive enhancing), medicinal neuropeptide complex that possesses neuroprotective and neurotrophic (nerve regenerating) repair properties.  It is a mixture of neuropeptides, including brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), ciliary neurotrophic factor (CNTF), and other neuropeptides.  Neuropeptides are used by neurons to communicate with each other.  

 

Cerebrolysin interacts with several pathways of intracellular signal communication.  The cellular integration of these peptide signals results in the observed neuroprotective and neurorestorative effects.  Cerebrolysin therapy is safe and well-tolerated by patients.

 

From a scientific perspective, these pathways regulate on a molecular level the cellular processes of neurogenesis, angiogenesis, dendrite arborization, axonal sprouting, myelination, and remodeling of the neurovascular unit, thereby supporting the maintenance and repair of the neuronal network in the brain.

 

 

Cerebrolysin Peptide Complex

 

Cerebrolysin has been proven to have a powerful, neurotrophic activity similar to nerve growth factors that promote peripheral and central neuronal stimulation. It improves efficiency within the brain’s aerobic metabolic processes and enhances intracellular peptide synthesis.  Cerebrolysin supports the brain's ability for self-repair by stimulating neuro-recovery. 

 

The potent, neuroprotective properties of Cerebrolysin help to shield neurons from metabolic acidosis, to prevent the formation of free radicals and protect against oxidative stress in the central nervous system (brain) and peripheral nervous system, and to decrease the neurotoxic action of certain amino acids and other environmental toxins.

 

Research has shown that it may reduce the neurodegenerative pathology in Alzheimer’s disease (AD), post-stroke, and post-acute traumatic brain injury.  Significant improvement of the cognitive function of patients on Cerebrolysin has been observed.

 

Cerebrolysin is used for the treatment of ischemic and hemorrhagic stroke, traumatic brain injuries (TBI), different forms of dementia (vascular dementia, Alzheimer’s disease), and cognitive disorders, and to prevent cognitive decline after brain injuries.  It prevents the formation of toxic protein aggregates (amyloidosis), and lowers the level of inflammatory processes in the brain, both linked to neurodegeneration.

 

Cerebrolysin Effects on Brain

 

Empirical observations by Integrative Medicine physicians using Cerebrolysin therapy for their patients with chronic pain syndromes have shown that it can provide significant, lasting, pain relief, when appropriately administered, for chronic pain due to arthritis, autoimmune disorders, peripheral neuropathy, and post-infectious, post-traumatic, and post-surgical injury to the nervous system.

 

Benefits of Cerebrolysin may include:

 

  • Improved Mental Function and Memory

  • Protection of the Brain from Oxidative Stress

  • Protection of the Brain from Damage by Toxins

  • Helps Repair the Brain and Nerves after Injury

  • Useful for Treatment of:

  • Different Forms of Dementia

  • Cognitive Disorders

  • Stroke

  • Traumatic Brain Injuries (TBI)

  • Prevention of Cognitive Decline after Any Brain Injuries

  • Helps Relieve Chronic Pain in Many Different Conditions:

  • Diabetic Neuropathy

  • Metabolic Neuropathy

  • Toxic and Post-Traumatic Neuropathy   

 

Thymosin Alpha 1

 

Thymic peptides, which are naturally produced in the thymus gland, promote physiological processes that include modulation of immune responses, i.e., both stimulation or suppression when needed, and can aid in the treatment of chronic, bacterial, viral, and fungal infections.  They also help promote the regulation of cell motility, neuroplasticity (ability of the brain to form and reorganize neural synaptic connections, esp. in response to learning or experience or following injury), angiogenesis (new blood vessel growth), repair and remodeling of blood vessels, heart cells, and other injured tissues, as well as stem cell differentiation.  

 

Benefits of Thymosin Alpha 1 may include:

 

  • Increases immune cell activity

  • Corrects immune system dysfunction

  • Normalizes immune balance and response

  • Stimulates T-Lymphocyte and Natural Killer cell production

  • Promotes the development of B-Lymphocytes into Plasma Cells

  • Decreases production of pro-inflammatory cytokines

  • Increases chemotactic response and phagocytosis by neutrophils

  • Improves host defense to infection

  • Inhibits viral replication

  • Improves tissue repair and healing

  • Reduces and normalizes inflammation

  • Improves stress tolerance

  • Improves microcirculation

  • Improves cancer defenses

  • Increases antioxidant and glutathione production

  • Reverses immunosuppression in CFS/FM/Lyme disease

 

Signs of low Thymosin Alpha 1 levels include:

 

  • Chronic fatigue, physical exhaustion, tired appearance, lack of motivation, apathy

  • Chronic infections (colds, Herpes, Hepatitis, Shingles, Lyme, and other severe infections)

  • Persistent illness, lack of full recovery, e.g., recurrent bouts of ‘flu-like’ symptoms, CFIDS

  • Easily injured joints, ligaments, tendons, and muscles with slow recovery

  • Chronic pain and disability after musculoskeletal trauma

  • Slow, difficult, and incomplete wound healing

 

Benefits of Thymosin Alpha 1 include:

 

  • Increases immune cell activity

  • Corrects immune system dysfunction

  • Normalizes immune balance and response

  • Stimulates T-Lymphocyte and Natural Killer cell production

  • Promotes the development of B-Lymphocytes into Plasma Cells

  • Decreases production of pro-inflammatory cytokines

  • Increases chemotactic response and phagocytosis by neutrophils

  • Improves host defense to infection

  • Inhibits viral replication

  • Improves tissue repair and healing

  • Reduces and normalizes inflammation

  • Improves stress tolerance

  • Improves microcirculation

  • Improves cancer defenses

  • Increases antioxidant and glutathione production

  • Reverses immunosuppression in CFS/FM/Lyme disease

 

Signs of low Thymosin Alpha 1 levels may include:

 

  • Chronic fatigue, physical exhaustion, tired appearance, lack of motivation, apathy

  • Chronic infections (colds, Herpes, Hepatitis, Shingles, Lyme, and other severe infections)

  • Persistent illness, lack of full recovery, e.g., recurrent bouts of ‘flu-like’ symptoms, CFIDS

  • Easily injured joints, ligaments, tendons, and muscles with slow recovery

  • Chronic pain and disability after musculoskeletal trauma

  • Slow, difficult, and incomplete wound healing

 

Thymosin Beta 4

 

 

Benefits of Thymosin Beta 4 may include:

 

  • Potent, anti-inflammatory for wounds, involving the muscles, joints, and skin

  • Helps to support stem cells to heal and regenerate injured tissues

  • Helps to promote rapid wound healing with little to no scarring

  • Enhances fibroblast cell activity and collagen deposition

  • Helps to prevent the formation of adhesions and fibrous bands in injured tissues, esp. in muscles, ligaments, tendons, joints, and skin

  • Protects and restores neurons in post-traumatic brain injury (TBI)

  • Helps to reduce acute or chronic pain and inflammation

  • Helps to promote improved flexibility of the body

  • Promotes hair growth and darkening of gray hair

 

 

 

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